Collagen Type I, Bovine, 10 mg

Highly Purified type I native collagen from bovine skin. Lyophilized   Type I collagen is the most abundant collagen and is found in connective tissues including tendon, ligament, dermis and blood...

Protein

8052010

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Highly Purified type I native collagen from bovine skin. Lyophilized

 

Type I collagen is the most abundant collagen and is found in connective tissues including tendon, ligament, dermis and blood vessel. It is the major component and the primary determinant of tensile strength of the extracelluar matrix (ECM). It is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells etc. In addition, collagen I can self-assemble into a 3-D superamolecular gel in vitro, making it an ideal biological scaffold to promote more in vivo-like cellular morphology and function.

Symbols/Related Terms:

  • COL1A1
  • COL1A2
  • osteogenesis imperfecta


Product Insert (PDF) - Informational use only. Please refer to insert included with product.

Data/Specifications: 

  • Reconstitution: Use 0.1 M acetic acid, pH 3.0
  • Purification: Partial pepsin digestion in acidic conditions and differential salt precipitation.
  • Source: Bovine (calf ) skin. Collagen was extracted from washed dissected tissue into dilute acetic acid after pepsin treatment. Collagen type I was purified by using differential salt precipitation.
  • Form: lyophilized, 10 mg/vial
  • Purity: Bovine Type I Collagen (90%) other non-collagen proteins (<0.5%)
  • Storage: Collagen dissolved in acetic acid is stable at 4 °C for 1 month. Lyophilized collagen long term storage (2 years) at -20°C or lower.