MonELISA® Collagen Type II Anti-Mouse IgG2b ELISA

The MonELISA® Collagen Type II (CII) Antibody ELISA kit is used to measure IgG2b antibodies generated against mouse type II collagen used in the induction of arthritis in mice in less...

ELISA

M036081

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For research use only. Not for use in diagnostic procedures.

The MonELISA® Collagen Type II (CII) Antibody ELISA kit is used to measure IgG2b antibodies generated against mouse type II collagen used in the induction of arthritis in mice in less than 3 hours. MonELISA® Ancillary Reagent Kit, Catalog Number M036080 (sold separately).

 

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The Collagen-induced arthritis (CIA) model is one of the most widely used models for the study of Rheumatoid Arthritis (RA). Collagen type II (CII) in adjuvant is used to induce arthritis by triggering autoreactive B cells, which play an important role in the development of arthritis. This B cell response to CII is strictly T cell dependent, where the B cells predominantly switch isotype to IgG.



Symbols/Related Terms:
- COL-2
- type II collagen antibody ELISA
- COL2A1
- pro-alpha 1(II) chain


    Product Insert (PDF) - Informational use only. Please refer to insert included with product.

    Data/Specifications:

    • Species: mouse
    • Sample Type: serum
    • Sample Preparation: 1:50
    • Sample Size: 100 uL
    • Sensitivity: 0.75 ng/mL.
    • Assay Length: < 3 hrs.