Lubricin Antibody, Bovine, 1 mL

Lubricin (PRG4) monoclonal antibody (mouse, clone 6A1) to detect superficial zone protein (SZP) from bovine articular cartilage and a non conformational epitope in the C terminus of lubricin. Clear-liquid. No preservatives....

Antibodies

1042015

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Lubricin (PRG4) monoclonal antibody (mouse, clone 6A1) to detect superficial zone protein (SZP) from bovine articular cartilage and a non conformational epitope in the C terminus of lubricin. Clear-liquid. No preservatives. Concentration is 0.1 mg/mL.

 

Lubricin is processed from the same gene as superficial zone protein, the proteoglycan 4 gene (PRG4). Lubricin is synthesized by synovial fibroblasts and secreted into the synovial fluid where its role is to regulate the lubrication of diarthrodial joints. Additionally, it is found in the meniscus, ligaments and tendons. Mutations in the lubricin gene are associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome.

Related Terms/Symbols

  • PRG4
  • Proteoglycan 4
  • SZP
  • Articular superficial zone protein
  • Megakaryocyte stimulating factor
  • Pericarditis syndrome
  • Q92954

 

References/Citations:

Seol, D., McCabe, D. J., Choe, H., Zheng, H., Yu, Y., Jang, K., ... & Martin, J. A. (2012). Chondrogenic progenitor cells respond to cartilage injury. Arthritis & Rheumatism, 64(11), 3626-3637.

Product Insert (PDF) - Informational use only. Please refer to insert included with product.

Data/Specifications: 

  • Concentration: 0.1 mg/mL
  • Immunogen: Purified SZP from bovine articular cartilage.
  • Clone: 6A1
  • Isotype: IgG
  • Host: Mouse
  • Purity: Protein G
  • Specificity: Recognizes SZP from bovine articular cartilage and a non-conformational epitope in the C terminus of lubricin.
  • Form: Clear Liquid; PBS, no preservatives
  • Storage: -20° C