Collagen Type IV Antibody, anti-Rat, 100 uL

Affinity chromatography purified rabbit antibody to rat type IV collagen extracted, purified from rodent tumor tissues. Purified, freeze-dried (0.5 ml). Reconstitute with 0.5 ml di H2O. Type IV collagen (CIV) is...

Antibodies

203005-1

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Affinity chromatography purified rabbit antibody to rat type IV collagen extracted, purified from rodent tumor tissues.

Purified, freeze-dried (0.5 ml). Reconstitute with 0.5 ml di H2O. Type IV collagen (CIV) is a major structural component of the basal lamina that assembles as a sheetlike network in the underlying extracellular space of all epithelial cells and tubes. The basal lamina separates the epithelia from the underlying connective tissue. There are several different isoforms of type IV collagen, but all are composed in a triple helical structure. The different isoforms are synthesized from six genes: COL4A1, COL4A2, COL4A3, COL4A4, COL4A5 and COL4A6. Type 1V collagens are considerably more flexible than the fibrillar type collagens. Mutations in genes associated with type IV collagen are associated with Alport and Goodpasture syndrome.

Product Insert (PDF) - Informational use only. Please refer to insert included with product.

Data/Specifications: 

Format: Purified, freeze-dried (0.5 ml). Reconstitute with 0.5 ml di H2O and store aliquots at -20°C.

Specificity (% at 1:15000 RIA dilution):
Rat Collagen, Type IV : 100%
Rat Collagen, Types I, II, III, V : < 0.1%
Human collagen type I: < 0.1%
Rat Fibronection : < 0.1%
Mouse Laminin: <0.1%